Clinical manifestations refer to the signs and symptoms that a patient presents with during a specific disease or medical condition. These manifestations are observable or measurable indicators that help healthcare professionals diagnose and monitor the progress of a patient's illness. In medical research, the study of clinical manifestations involves examining the various physical, cognitive, emotional, and behavioral symptoms associated with a particular disease or condition. This research area focuses on understanding how these manifestations manifest in patients, how they may vary among different individuals, and how they can be effectively managed and treated. Overall, studying clinical manifestations is crucial for improving our understanding of diseases and their progression, as well as for developing more accurate diagnostic and treatment strategies to improve patient outcomes.